A Small Molecule May Block Zika Virus Infections

From Zika News
October 20, 2019

A recent study found a new small molecule has the ability to block Zika virus infection in human cells (in vitro) and in mice (in vivo).

This molecule, 6-deoxyglucose-diphyllin (DGP), is a broad-spectrum antiviral that potentially blocks infection by Zika viruses.

And, DGP may also inhibit human infections by other flaviviruses. 

This study published in EbioMedicine in September 2019, reported the DGP molecule targets the cellular endosomal acidification, preventing the entry of the virus into the cell, consequentially inhibiting infection.

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